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Canon EF body + Pentax 645 lens


You can mount a P645 medium format on an EF, but you'll have to keep some things in mind.

Medium format systems differ in many aspects from the usual 35 mm ones. Multipliers, focal points, sensor/tape sizes are all different (actually, medium format means larger than 35 mm but smaller than large format, therefore "medium format" doesn't define an exactly defined size).

Nothing can stop you from mounting a P645 medium format lens on an EF bayonet lock system, adapters are also available:

Kipon released a lens turbo solution for coupling the two systems. With the help of some extra optics "shrink" the M645 medium format size image to fullframe size, eliminating the crop factor.

A P645-EF adapter released by Vizelex has built-in ND filter:

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In terms of compatibility, we distinguish four separate categories:

This means that you'll be able to apply the lens on the camera in question with a proper adapter, and full focus range will be available with it (often with aperture control too). If AF is supported, you'll see it in the description.
This means that due to the flange focal depth or other factor this conversion would be normally unfeasible, but with some compromises (e.g. using a speedbooster adapter) can be made possible.
This means that the flange focal depth should make mounting and using inifinty focus possible, but for some reason there are no adapter rings available or other factors make it unviable.
This means that you won't be able to mount your lens due to mechanical incompatibility or the difference in flange focal depth doesn't make inifinity focus possible. Although numerous lenses can be mounted on cameras without infinity focus, but this cannot be considered actual compatibility.

Additional information for compatible variations:

manual focus (on the lens, with its own control ring)
autofocus available (AF controlled by the camera body)
manual aperture control (on the lens, with its own control ring)
automatic aperture control (controlled by the camera body)
speedbooster (focal reducer) adapters are available
macro (variable length) adapters are available
tilt-shift (or other flexible) adapters can be used

If you'd like to read more in-depth about compatiblity, you'll need to get familiar with flange focal depth, see this article.