Canon EF body + Pentax 645 lens
COMPATIBLE MF MA SB
You can mount a P645 medium format on an EF, but you'll have to keep some things in mind.
Medium format systems differ in many aspects from the usual 35 mm ones. Multipliers, focal points, sensor/tape sizes are all different (actually, medium format means larger than 35 mm but smaller than large format, therefore "medium format" doesn't define an exactly defined size).
Nothing can stop you from mounting a P645 medium format lens on an EF bayonet lock system, adapters are also available:
Kipon released a lens turbo solution for coupling the two systems. With the help of some extra optics "shrink" the M645 medium format size image to fullframe size, eliminating the crop factor.
A P645-EF adapter released by Vizelex has built-in ND filter:
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